Computer modeling for pharmacological treatments for dystonia

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Computer modeling for pharmacological treatments for dystonia.

Dystonia is a movement disorder that produces involuntary muscle contractions. Current pharmacological treatments are of limited efficacy. Dystonia, like epilepsy is a disorder involving excessive activty of motor areas including motor cortex and several causal gene mutations have been identified. In order to evaluate potential novel agents for multitarget therapy for dystonia, we have develope...

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ژورنال

عنوان ژورنال: Drug Discovery Today: Disease Models

سال: 2016

ISSN: 1740-6757

DOI: 10.1016/j.ddmod.2017.02.003